The Hypothalamus, Pituitary Glands and Hormones! And not the Sex Pheromone Variety…

The Hypothalamus and the pituitary gland are super important in regulating the hormone release from one other gland in the body.
The Hypothalamus is the link between the Endocrine and Nervous System, It also controls the Pituitary Gland through 9 releasing and inhibiting hormones. Together the Pituitary Gland and the Hypothalamus regulate all aspects of growth, development, metabolism and homeostasis. The Pituitary Gland secretes several hormones that the Hypothalamus generates (synthesises).

For example the Pituitary Gland and the hypothalamus are involved in Thyroid Function.
The Hypothalamus produces TRH  – Thyrotropin releasing Hormones when the thyroid hormone level drops in the body. This causes the secretion of TSH – Thyroid stimulating Hormone from the Pituitary Gland. This causes the Thyroid to produe more T3 and T4 Hormones which raise the level in the blood – The Pituitary Gland will then lower the amount of TSH in the blood.


ADH – Antidiuretic Hormone – Vasopressin

ADH is produced in the Hypothalamus and released in the posterior pituitary (Posterior Lobe/Neurophypophysis) as a response to dehydration.

Antidiuretic Hormone stimulates water reabsorption by the kidneys and arteriolar constriction. General Function is vasopressin – conserving water. ADH (is released) kicks in during dehydration –  decreases urine production and sweating and increases blood pressure as a result of vasoconstriction. ADH is controlled by the osmotic pressure in the blood. And during over hydration ADH is inhibited.

Dehydration:

  1. Hypothalamic osmoreceptors are stimulated by High Blood Osmotic pressure
  2. Osmoreceptors activate the neurosecretory cells that synthesis and release ADH
  3. Nerve impulses free ADH from axon terminals in the Pituitary Gland into the bloodstream
  4. Kidneys retain more water – decreases urine volume, Sweat Glands decrease water loss and Arterioles constrict – increased BP

Overhydration:

  1. Low Blood Osmotic Pressure inhibits hypothalamic osmoreceptors
  2. Then this impacts on the ADH secretion as osmoreceptors are inhibited
  3. Which effects, sweat, urine and blood pressure.

January 5th Annual Day Of Rejection

January 5th Annual Day Of Rejection

I wish I was joking, but every 5th of January since 2011 I have always been dumped on this day or faced the sharp pain of rejection.

The first time was when my high school boyfriend of two months broke up with me, before we started our last year of school together. Jan 5th 2011

Then again the following year, a guy who I was infatuated with, Bas, decided that after a month things were moving too fast, Jan 5th 2012.

Lucky number three, wasn’t so lucky, I admit I realised there was a pattern starting to develop and I thought this guy was different. My infatuation with Bas, pulled me out yet another relationship, only to have my heart torn out again. Jan 5th 2013

Number 4, he was a weird guy, who refused to date me since my morals were too ‘loose’, but was more than happy to revel in them.  Jan 5th 2014

And number 5, Well it will be interesting to see if by avoiding my phone and men I will be able to avoid the rejection. I always say I am staying away from men and not even leaving the house on the 5th of January, but somehow I always put my faith in these guys that they will be the one, or something different.

Keeping in mind I have been dumped on other dates during the years, it is just a little odd that it happens like this the past few years.

So everyone else out there, enjoy your 5th of Jan in style, I will be on lock down with icecream and movies tomorrow.

Flight or Fight?

The Autonomic Nervous System usually operates without conscious control, it is regulated by the hypothalamus and the brain stem. The efferent parts of the ANS are divided into the Sympathetic and the Parasympathetic. Some organs in the body receive impulses from both of these, this is called dual innervation.

The Sympathetic system takes over in any physical or mental stress, for example;

  • exercise,
  • embarrassment,
  • excitement
  • and emergency.

It is accompanied by the body getting ready to implement the fight or flight response, this means:

  • dilation of pupils
  • increase of heart rate and blood pressure
  • decrease in blood flow to nonessential organs (e.g. focus away from digesting food)
  • increase in blood flow to skeletal & cardiac muscle
  • airways dilate & respiratory rate increases
  • and blood glucose level increase

I can identify a few times when the fight or flight response kicked in,

A few weeks ago two men tried to break into the secure building I live in at 3am, my body was flooded with adrenaline and cortisol even though I knew I was safe. I could feel my heart racing and suddenly had such amazing energy even though I had just been woken up at 3 am by breaking tiles. I went out and started to yell at them, and ended up man handling one of them, not realising that I felt somewhat stronger than usual, I ended up piercing the skin when I grabbed one guy by the arm which I didn’t notice until after the fiasco.

On reflection,  I wouldn’t actually be threatening to two very intoxicated big burly men. It took around an hour for my body to calm down afterwards and I felt like I really needed to go for a run or do something to expel all the excess energy.